The fatigue behaviour of structural CFRP bonds is significantly influenced by the surface of the joined parts, among other things. Therefore, this study investigates the influence of the macro- and microscopic topography of the interface, which is generated by peel plies, release films or surface pretreatment methods. Measurements with high-resolution 2D image correlation and acoustic emission during the test allow to draw conclusions about the crack initiation and crack propagation phase and contribute to the identification of the failure mechanisms in addition to the fracture surface investigation.